Aripiprazole Levels and Effects while Breastfeeding Summary of Use during Lactation Limited information indicates that maternal doses of aripiprazole up to 15 mg daily produce low levels in milk, but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
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Abilitat, Aripiprazol, Aripiprazolum, OPC 31, Opc 14597 A quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent antagonistic activity on serotonin 5-HT2A receptors.
The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Suggested therapeutic alternatives to those drugs are provided, where appropriate.
Breastfeeding Toddler + Abilify and Lamictal 11-03-2014, 09:25 PM ... then weaning off abilify. I'm currently breastfeeding my 15 month old toddler. She's about 20lbs. She nurses no more than 4 times a day, about 5-10 minutes each but usually it's once in the morning, once in the afternoon, and rarely at night. ...
Clozapine is concentrated in the breast milk 72,77 and has been known to cause sedation, decreased suckling, restlessness or irritability, seizures, and cardiovascular instability in the breastfeeding infant. 72 Given the potential for serious adverse consequences to infants who are exposed to clozapine, breast-feeding should be avoided when maternal clozapine therapy is indicated.
Aripiprazole Breastfeeding Warnings. Use is not recommended; a decision should be made to discontinue breast-feeding or discontinue the drug, taking into account the importance of the drug to the mother. Excreted into human milk: Yes Comment: The effects on lactation and in the nursing infant are unknown.
Monitoring of the infant is encouraged, as there has been one report of an infant who had sedation on a higher dose of olanzapine, which resolved after the mother’s dose was halved to 5mg/day. To date, there have been no reports on the use of the antipsychotic medications, ziprasidone (Geodon) and aripiprazole (Abilify) while breastfeeding.
A 2014 systematic review concluded that add-on therapy with low dose aripiprazole is an effective treatment for obsessive-compulsive disorder that does not improve with SSRIs alone. The conclusion was based on the results of two relatively small, short-term trials, each of which demonstrated improvements in symptoms.